abstract：BACKGROUND:There have been conflicting reports comparing the prevalence of large polyps (>9 mm) between Hispanics and non-Hispanic whites (NHW). Differences between Hispanic subpopulations may account for these variations. AIMS:We aimed to assess the prevalence of large polyps (>9 mm) in Hispanics from Mexican- and no...

journal_title：Digestive diseases and sciences

authors： Avalos DJ,Zuckerman MJ,Dwivedi A,Dodoo C,Satiya J,Castro FJ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Wnt-β-catenin signaling is essential for homeostasis of intestinal stem cells in mice and is thought to promote intestinal crypt fission. AIMS:The aim of this study was to investigate Wnt-β-catenin signaling in intestinal crypts of human infants. METHODS:Duodenal biopsies from nine infants (mean, range 0.9...

journal_title：Digestive diseases and sciences

authors： Dudhwala ZM,Drew PA,Howarth GS,Moore D,Cummins AG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Approximately 10% of children with celiac disease (CD) have ultra-short celiac disease (USCD), where histological abnormalities are limited to the duodenal bulb. The aim of our retrospective study was to identify clinical and serological characteristics at baseline and at follow-up of children with ...

journal_title：Digestive diseases and sciences

authors： Doyev R,Cohen S,Ben-Tov A,Weintraub Y,Amir A,Galai T,Moran-Lev H,Yerushalmy-Feler A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:A new device with metallic wires for scrape cytology was developed. AIMS:To compare the diagnostic performance of scrape cytology and conventional cytology during endoscopic retrograde cholangiopancreatography for biliary strictures. METHODS:A total of 420 cases with biliary stricture underwent transpapill...

journal_title：Digestive diseases and sciences

authors： Nakahara K,Michikawa Y,Morita R,Suetani K,Morita N,Sato J,Tsuji K,Ikeda H,Matsunaga K,Watanabe T,Matsumoto N,Kobayashi S,Otsubo T,Itoh F

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in affluent countries. Recent studies have reported that circular RNAs (circRNAs) are important regulators of hepatic steatosis. However, the role and mechanism of circRNA in NAFLD are poorly understood. AIMS:This study is to ...

journal_title：Digestive diseases and sciences

authors： Li P,Shan K,Liu Y,Zhang Y,Xu L,Xu L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Colonoscopy is associated with multiple adverse outcomes. With an aging population undergoing colorectal cancer screening, few modalities exist to assess the patient risk prior to colonoscopy. Frailty, the age-related decline in reserve and function across multiple organ systems, predicts poor surgical outco...

journal_title：Digestive diseases and sciences

authors： Taleban S,Toosizadeh N,Junna S,Golden T,Ghazala S,Wadeea R,Tirambulo C,Mohler J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a common disease with intestinal dysmotility, whose mechanism remains elusive. TMEM16A is a calcium-activated chloride channel (CaCC) involved in intestinal slow-wave generation. AIMS:To investigate whether TMEM16A is involved in colonic dysmotility in IBS. METHODS:A rat m...

journal_title：Digestive diseases and sciences

authors： Lin MJ,Yu BP

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Triglyceride-rich lipoproteins are important in dietary lipid absorption and subsequent energy distribution in the body. Their importance in the gut-lymph may have been overlooked in sepsis, the most common cause of critical illness, and in gut ischemia-reperfusion injury, a common feature of many critical i...

journal_title：Digestive diseases and sciences

authors： Hong J,Nachkebia S,Tun SM,Petzer A,Windsor JA,Hickey AJ,Phillips AR

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Concanavalin A is known to activate T cells and to cause liver injury and hepatitis, mediated in part by secretion of TNFα from macrophages. Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors have been shown to prevent tissue damage in various animal models of inflammation. The objectives of this stu...

journal_title：Digestive diseases and sciences

authors： Wardi J,Ernst O,Lilja A,Aeed H,Katz S,Ben-Nachum I,Ben-Dror I,Katz D,Bernadsky O,Kandhikonda R,Avni Y,Fraser IDC,Weinstain R,Biro A,Zor T

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Evidence of humanistic detriments of Clostridium difficile infection (CDI) remains limited. AIMS:To assess humanistic burden associated with CDI. METHODS:Self-reported National Health and Wellness Survey data between 2013 and 2016 were analyzed for the USA, five European countries, China, and Brazil. Outco...

journal_title：Digestive diseases and sciences

authors： Heinrich K,Harnett J,Vietri J,Chambers R,Yu H,Zilberberg M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND AIM:Vascularity is a critical feature in the evaluation of pancreatic neuroendocrine tumor (PNET). When done by EUS, contrast agents are recommended. However, vascular architecture (VA) can also be evaluated by routine Doppler flow in EUS without contrast agents. Our aim was to provide a simple VA classi...

journal_title：Digestive diseases and sciences

authors： Chen K,Zhang W,Zhang Z,He Y,Liu Y,Yang X

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND AIM:Previous studies evaluating the safety of endoscopic retrograde cholangiopancreatography (ERCP) in patients with end-stage renal disease (ESRD) undergoing hemodialysis reported an increased risk of post-procedural bleeding. We investigated the safety and efficacy of ERCP for the treatment of choledoc...

journal_title：Digestive diseases and sciences

authors： Kim SB,Kim KH,Kim TN

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Obesity and metabolic syndrome are risk factors for colorectal neoplasia (CRN). However, the association between metabolically healthy obese (MHO) or metabolically unhealthy non-obese (MUNO) status and the risk of CRN remains unclear. AIMS:We aimed to elucidate the association between MHO or MUNO status and...

journal_title：Digestive diseases and sciences

authors： Kim NH,Jung YS,Park JH,Park DI,Sohn CI

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Average-risk women aged 50-59 years have a lower incidence and mortality of colorectal cancer relative to age-matched men, calling into question the benefit of screening colonoscopy in this age group. AIMS:We aimed to determine whether FOBT is an effective initial screening test in 50-59-year-old women. ME...

journal_title：Digestive diseases and sciences

authors： Mooers HM,Holub JL,Lieberman DA

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Split dose bowel preparations (SDP) have superior outcomes for colonoscopy as compared to evening before regimens. However, the association of the actual volume of the SDP to colonoscopy outcome measures has not been well studied. AIMS:Compare adenoma detection rate (ADR), sessile serrated polyp detection r...

journal_title：Digestive diseases and sciences

authors： Siddiki H,Ravi S,Al-Qaisi MT,Fath AR,Ramirez F,Crowell MD,Pannala R,Faigel DO,Gurudu SR

更新日期：2018-09-01 00:00:00

abstract：:The original version of the article unfortunately contained tagging error in first and family name of authors Ariella Bar-Gil Shitrit and Ami Ben Ya'acov. This has been corrected with this erratum. ...

journal_title：Digestive diseases and sciences

authors： Bar-Gil Shitrit A,Cohen Y,Hassin O,Ben Ya'acov A,Farkash R,Koslowsky B,Milgrom Y,Livovsky DM,Samueloff A,Goldin E,Grisaru-Granovsky S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Transmembrane and ubiquitin-like domain-containing 1 protein (Tmub1) negatively regulates liver regeneration. However, whether this regulation involves posttranscriptional modification of Tmub1 expression is unknown. AIM:The aim of the study was to investigate whether microRNA (miR)-27a/b regulates posttran...

journal_title：Digestive diseases and sciences

authors： Lan X,Li G,Liu H,Fu H,Chen P,Liu M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis are at high readmission risk. Using a large statewide database, we evaluated the effect of hospital cirrhosis-related patient volume on 30-day readmissions in patients with cirrhosis. METHODS:We conducted a retrospective study of the Healthcare Cost and Utilization Project State Inpa...

journal_title：Digestive diseases and sciences

authors： Wei M,Ford J,Li Q,Jeong D,Kwong AJ,Nguyen MH,Chang MS

更新日期：2018-09-01 00:00:00

abstract：:Over the past two decades, evidence has accumulated to challenge the traditional view that cardiac mucosa, which is comprised exclusively of mucus glands, is the normal lining of the most proximal portion of the stomach (the gastric cardia). There is now considerable evidence to suggest that cardiac mucosa develops as...

journal_title：Digestive diseases and sciences

authors： Spechler SJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...

journal_title：Digestive diseases and sciences

authors： Fabian O,Hradsky O,Drskova T,Mikus F,Zamecnik J,Bronsky J

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Adenosine deaminase acting on RNA 1 (ADAR1) is known to mediate deamination of adenosine-to-inosine through binding to double-stranded RNA, the phenomenon known as RNA editing. Currently, the function of ADAR1 in gastric cancer is unclear. AIMS:This study was aimed at investigating RNA editing-dependent and...

journal_title：Digestive diseases and sciences

authors： Cho CJ,Jung J,Jiang L,Lee EJ,Kim DS,Kim BS,Kim HS,Jung HY,Song HJ,Hwang SW,Park Y,Jung MK,Pack CG,Myung SJ,Chang S

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND/AIMS:There is a lack of studies describing the epidemiology of colorectal cancer (CRC) in patients aged 75 years and older (elderly). Current guidelines recommend against routine screening colonoscopies in this population. We sought to describe the epidemiology of CRC in the elderly, utilizing a large, popul...

journal_title：Digestive diseases and sciences

authors： Chouhan V,Mansoor E,Parasa S,Cooper GS

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Obesity is associated with NAFLD, and bariatric surgery has significant impact on this liver disease, with reported improvement in hepatic fibrosis. AIMS:To investigate the effects of bariatric surgery on long-term liver disease-related outcome in obese patients with nonalcoholic fatty liver disease (NAFLD)...

journal_title：Digestive diseases and sciences

authors： Giannini EG,Coppo C,Romana C,Camerini GB,De Cian F,Scopinaro N,Papadia FS

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Approximately 233,898 individuals in the Veterans Affairs healthcare network are hepatitis C virus (HCV)-infected, making the Veterans Affairs the single largest provider of HCV care in the USA. Direct-acting antiviral treatment regimens for HCV offer high cure rates. However, these medications pose an enorm...

journal_title：Digestive diseases and sciences

authors： Maier MM,Zhou XH,Chapko M,Leipertz SL,Wang X,Beste LA

更新日期：2018-06-01 00:00:00

abstract：:The original version of this article unfortunately contained an error in a couple of reference citation in Discussion Section, paragraph 6. The reference citation number should be changed from [6] to [9] in the below sentences so that it reads. ...

journal_title：Digestive diseases and sciences

authors： Hammer V,Hammer K,Memaran N,Huber WD,Hammer K,Hammer J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Avoidance of gluten is critical for individuals with celiac disease (CD), but there is also concern that "extreme vigilance" to a strict gluten-free diet may increase symptoms such as anxiety and fatigue, and therefore, lower quality of life (QOL). We examined the associations of QOL with energy lev...

journal_title：Digestive diseases and sciences

authors： Wolf RL,Lebwohl B,Lee AR,Zybert P,Reilly NR,Cadenhead J,Amengual C,Green PHR

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) are often immunosuppressed, and those patients receiving anti-tumor necrosis factor α (TNF) therapy can have lower antibody responses to vaccines. Pertussis cases are at their highest levels in the post-vaccine era. There is little data regarding responses to th...

journal_title：Digestive diseases and sciences

authors： Caldera F,Saha S,Wald A,Garmoe CA,McCrone S,Megna B,Ley D,Reichelderfer M,Hayney MS

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Histological remission represents a target distinct from endoscopic healing in ulcerative colitis (UC) and seems a better predictor of clinical outcomes. AIMS:The aim of this study was to assess the ability of adalimumab to achieve histological remission in UC patients. METHODS:Single-center, retrospective...

journal_title：Digestive diseases and sciences

authors： Fernández-Blanco JI,Fernández-Díaz G,Cara C,Vera MI,Olivares D,Taxonera C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Acid reflux has been associated with poor outcomes following lung transplantation. Unlike surgical fundoplication, the role of noninvasive, pharmacologic acid suppression remains uncertain. AIMS:To assess the relationship between post-transplant acid suppression with proton pump inhibitors (PPI) or histamin...

journal_title：Digestive diseases and sciences

authors： Lo WK,Goldberg HJ,Boukedes S,Burakoff R,Chan WW

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Ulcerative colitis (UC) patients with progression of their disease despite optimized medical therapy may warrant "curative" proctocolectomy with end ileostomy or ileo-anal pouch (IPAA) anastomosis. The aim of our study was to assess the incidence of later recurrent ileitis that lead to altering the ...

journal_title：Digestive diseases and sciences

authors： Shamah S,Schneider J,Korelitz BI

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Liver fibrosis stage determines risk of morbidity and mortality from chronic hepatitis C virus (HCV) infection. Prior data have shown long-term reversal of liver fibrosis, measured by vibration-controlled transient elastography (VCTE), in patients successfully treated with interferon-based therapies. AIM:Ou...

journal_title：Digestive diseases and sciences

authors： Chan J,Gogela N,Zheng H,Lammert S,Ajayi T,Fricker Z,Kim AY,Robbins GK,Chung RT

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Thymoquinone (TQ) is the major constituent of Nigella sativa seed and has shown biological activity in various human carcinomas. However, few studies have reported its effect on esophageal carcinoma (EC). AIMS:To explore the chemosensitive effect and mechanism of TQ in augmentation of cisplatin (DDP)-induce...

journal_title：Digestive diseases and sciences

authors： Hu X,Ma J,Vikash V,Li J,Wu D,Liu Y,Zhang J,Dong W

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Safety-net hospitals are enriched in ethnic minorities and provide opportunities for high-impact hepatitis B virus (HBV) screening. AIM:We aim to evaluate the impact of a pilot program integrating HBV screening into outpatient endoscopy among urban safety-net populations. METHODS:From July 2015 to May 2017...

journal_title：Digestive diseases and sciences

authors： Campbell B,Lopez A,Liu B,Bhuket T,Wong RJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Prior studies have shown poor compliance with quality measures for IBD at academic and private practices. We sought to provide focused interventions to improve compliance and documentation with the IBD measures. METHODS:Two centers, academic practice (AP) and private practice (PP), initially reviewed their ...

journal_title：Digestive diseases and sciences

authors： Feuerstein JD,Papamichael K,Popejoy S,Nadelson A,Lewandowski JJ,Geissler K,Martinez-Vazquez M,Leffler DA,Ariyabuddhiphongs K,Thukral C,Cheifetz AS

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIM:Diabetes is the main cause of gastroparesis accompanying decreased neuronal nitric oxide synthase (nNOS) in myenteric ganglia of the stomach. Decreased nNOS expression in the stomach also results from defects in apolipoprotein E (ApoE), which is secreted by astrocytes and has neuroprotective effects ...

journal_title：Digestive diseases and sciences

authors： Fukuhara S,Masaoka T,Nishimura S,Nakamura M,Matsuzaki J,Tsugawa H,Miyoshi S,Mori H,Kawase S,Shibata S,Okano H,Kanai T,Suzuki H

更新日期：2017-12-01 00:00:00

abstract：:Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

journal_title：Digestive diseases and sciences

authors： Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:miR-30a expression is down-regulated and regulates tumor suppressors in various cancers. AIM:We investigated the mechanisms underlying the biological role of miR-30a in CRC. METHODS:MicroRNA, mRNA, and protein expression were analyzed by quantitative real-time PCR and Western blot. The migration and invasi...

journal_title：Digestive diseases and sciences

authors： Liu YC,Park YR,Kim SL,Lee ST,Kim SW

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Eradication therapies for Helicobacter pylori infection are advancing as new acid inhibitory reagents approved. The aim of this study was to assess the efficacy and safety of vonoprazan-based triple treatment. MATERIALS AND METHODS:Triple therapy with vonoprazan and two antibiotics (amoxicillin and clarithr...

journal_title：Digestive diseases and sciences

authors： Tanabe H,Ando K,Sato K,Ito T,Goto M,Sato T,Fujinaga A,Kawamoto T,Utsumi T,Yanagawa N,Ichiishi E,Otake T,Kohgo Y,Nomura Y,Ueno N,Sugano H,Kashima S,Moriichi K,Fujiya M,Okumura T

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:ESD allows higher rates of en-bloc and R0 resections, but has occasionally complications such as aspiration pneumonia. Factors associated with aspiration pneumonia are not completely understood. AIMS:To analyze the relationship between aspiration pneumonia and preoperative factors including pulmonary functi...

journal_title：Digestive diseases and sciences

authors： Matsumi A,Takenaka R,Ando C,Sato Y,Takei K,Yasutomi E,Okanoue S,Oka S,Kawai D,Kataoka J,Takemoto K,Tsugeno H,Fujiki S,Kawahara Y

更新日期：2017-11-01 00:00:00